Abstract
An investigation of the European Antimicrobial Resistance Genes Surveillance Network (EURGen-Net) detected the same mosaic IncHI1B(pNDM-MAR) resistance (OXA-48) and virulence (aerobactin) plasmid in 492 Klebsiella pneumoniae isolates from eight European Union countries during 2019-2024. Involvement of various K. pneumoniae sequence types (STs), multiple introductions, followed by large clonal outbreaks of three STs (ST147, ST392, ST45) carrying the plasmid in two countries indicate a high risk for further spread of this plasmid and a potential for difficult-to-treat K. pneumoniae infections to rise.