Development of a TaqMan multiplex PCR assay for detection of plasmid-mediated ampC β-lactamase genes

开发用于检测质粒介导的ampC β-内酰胺酶基因的TaqMan多重PCR检测方法

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Abstract

A multiplex, real-time TaqMan assay was designed to identify clinical isolates carrying plasmid-mediated ampC genes. The specificity and sensitivity of this assay were 100% when testing characterized AmpC/non-AmpC-producing isolates and randomly selected clinical isolates. This is a rapid assay that can be performed in a clinical microbiology laboratory.

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