Anti-inflammatory and antioxidant property of a novel floral mouthwash

一种新型花香漱口水的抗炎和抗氧化特性

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Abstract

It is of interest to prepare and evaluate the antioxidant and anti-inflammatory activity of a novel Clitoria ternatea and Matricaria chamomilla infused mouthwash. The floral extract using the two flowers in dried form was prepared in concentrations of 10µL, 20µL, 30µL, 40µL and 50µL. To assess the antioxidant activity, DPPH assay was done with L-ascorbic acid as the control agent. The anti-inflammatory activity of the floral extract was assessed by the Albumin Denaturation Assay for which diclofenac sodium was used. The absorbance value of the floral extract was determined for each of the concentrations for the antioxidant and anti-inflammatory properties. After 50 µL the prepared extract began to show close absorbance values compared to the standard solutions; at this concentration, the mouthwash was prepared. The preparation and evaluation of the floral extract of Clitoria ternatea and Matricaria chamomilla infused mouthwash shows promising anti-inflammatory and antioxidant properties and can be used as an adjunct in oral hygiene practices to reduce gingival inflammation. Further clinical studies using the prepared mouthwash are needed to test its efficacy.

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