Abstract
The constant entry of exogenous reactive oxygen species makes cigarette smoking one of the key contributors to systemic oxidative stress. Therefore, it is interest to compare the oxidative stress markers and lipid profiles of chronic smokers and age matched non-smokers. A cross-sectional examination of 200 males showed that serum Malondialdehyde (MDA) level was much higher and the SOD and CAT activities were much lower among smokers. Dyslipidemia and higher Atherogenic Index of Plasma were strongly positively related to oxidative stress. Thus, those oxidative biomarkers are potential cardiovascular risk predictors in chronic smokers.