Abstract
2D:4D ratio is the ratio of the lengths of the index and ring fingers. It is a potential indicator of prenatal hormonal exposure, reflecting androgen sensitivity and it may influence skeletal and dental growth. Therefore, it is of interest to explore the correlation between the 2D:4D ratio and malocclusion types using Angle's classification of malocclusion in 410 male students aged 12-15 years from Alrass City, Saudi Arabia. Statistical analysis using Chi-Square tests revealed no considerable association between the 2D:4D ratio and malocclusion type (p=0.904). This data suggest that the ratio does not serve as a reliable predictor highlighting the complexity of factors influencing malocclusion and the need for further studies to better interpret hormonal, genetic and environmental contributions to craniofacial growth.