Abstract
Sepsis is a life-threatening condition requiring early diagnosis and severity assessment in the emergency department (ED) to guide timely interventions. Therefore, it is of interest to evaluate the Modified Shock Index (MSI) as a prognostic tool for sepsis and compared its sensitivity and specificity to the quick sequential organ failure assessment (qSOFA) score in 150 sepsis patients, based on Sepsis-3 guidelines. Clinical data, including MSI and qSOFA scores, were collected at admission and patient outcomes were analyzed for mortality and hospital stay duration. An MSI cut-off of 1.28 predicted mortality with high accuracy (AUC 0.946, sensitivity 91.76%, specificity 90.77%), outperforming the qSOFA score (AUC 0.840). MSI is a reliable, easy-to-use bedside tool that surpasses the quick sequential organ failure assessment score in predicting sepsis prognosis, aiding in early identification and management of high-risk patients.