Assessment of chronic liver disease using shear wave elastography: Correlation with serum markers

利用剪切波弹性成像技术评估慢性肝病:与血清标志物的相关性

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Abstract

Chronic liver disease requires accurate fibrosis assessment, with non-invasive tools gaining importance over biopsy. Hence, this cross- sectional study evaluated liver fibrosis in 122 CLD patients using shear wave elastography (SWE) and correlated findings with serum markers. SWE showed strong correlation with APRI (r=0.70) and platelet count (r=-0.70), and moderate correlations with AST and FIB-4. Optimal SWE cutoffs were 9.2 kPa for significant fibrosis and 15.38 kPa for cirrhosis, with excellent diagnostic accuracy (AUROC=0.99). SWE combined with serum markers-especially APRI-provides a reliable, non-invasive alternative for fibrosis assessment in CLD patients.

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