Abstract
The anticancer potential of Vallisneria spiralis Linnaeus (Vallisneria spiralis L.) for human breast cancer management is of interest. In vitro shows that increasing concentrations of Vallisneria spiralis silver nanoparticles (AgNPs) and iron oxide nanoparticles (IONPs) resulted in greater cytotoxicity against MCF-7 breast cancer cells. The antioxidant potential of Vallisneria spiralis L. was assessed using 2-diphenyl-1-picryl-hydroxyl (DPPH) radical scavenging assay. Further molecular docking analysis of phytocompounds from Vallisneria spiralis L. with the target protein (PDB ID: 3CZH) shows optimal binding features. Thus, cytotoxicity analysis of Vallisneria spiralis for breast cancer with molecular docking of its phytochemicals and a target protein 3CZH is reported for further consideration.