Molecular modelling and docking analysis of a modelled trmB protein from Pseudomonas aeruginosa with selected chemical compounds

利用选定的化合物对铜绿假单胞菌的 trmB 蛋白进行分子建模和对接分析

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Abstract

Antimicrobial resistance (AMR) threatens global health with rising antibiotic-resistant infections, requiring novel antimicrobial targets. Therefore, it is of interest to report the molecular modeling and docking analysis trmB from Pseudomonas aeruginosa with suitable compounds. We show two compounds (5136 and 9865603) from the chemical library have optimal binding with the modelled trmB from Pseudomonas aeruginosa for further consideration.

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