Abstract
The potential of Bio-Oss® collagen xenograft for treating intrabony defects using minimally invasive surgical methods is of interest. Hence, 30 defect sites in individuals with mild to severe chronic periodontitis were investigated. Participants were randomly divided into two groups of 15 each. Group A underwent regenerative MIST (minimally invasive surgical technique) with a bovine-derived xenograft, while Group B received only MIST. Periodontal parameters, including plaque index, gingival index, probing pocket depth, clinical attachment levels, and intrabony defect fill, were evaluated at three and six-month intervals. Significant improvements in periodontal parameters were observed in both groups, with Group A showing significantly better results.