Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove

从皮查瓦拉姆红树林分离的链霉菌BDUSMP 02中非核糖体肽合成酶(NRPS)腺苷酸结构域的系统发育分析及其抗菌潜力

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Abstract

Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-domain in the Streptomyces sp BDUSMP 02. The result suggests that Streptomyces sp BDUSMP 02 has the potential to produce a new type of antibacterial compounds belonging to NRPS type.

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