Specific gene hypomethylation and cancer: new insights into coding region feature trends

特定基因低甲基化与癌症:编码区特征趋势的新见解

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Abstract

Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.

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