Abstract
A 50-year-old female, presented with severe dyspnoea and dysphagia only to solids. Chest-computed tomography (CT) scan revealed a giant bilateral intrathoracic mass in posterior mediastinum causing marked shift in the midline structures, squeezing the heart to sternum. CT-guided biopsy showed lipoma. The patient underwent left posterolateral thoracotomy for surgical removal of entire mass weighing 6 kg and measured 42 × 25 × 10 cm, with histologic examination reported as liposarcoma grade 1. It is the largest surgically treated intrathoracic liposarcoma documented in the modern literature.