Noninvasive evaluation of the chronic influence of local air velocity from an air conditioner using salivary cortisol and skin caspase-14 as biomarkers of psychosomatic and environmental stress

使用唾液皮质醇和皮肤 caspase-14 作为心身和环境压力的生物标志物,无创评估空调局部风速的慢性影响

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作者:M Yamaguchi, H Nishimiya

Conclusion

The effects of chronic exposure to air movement generated by an air conditioner may be quantified by measurement of salivary cortisol and skin caspase-14.

Methods

Over a consecutive 5-day period, 16 healthy young male adults were exposed to air flow from a whole ceiling-type air conditioner (low local air velocity) and from a commercial concentrated exhaust air conditioner (high local air velocity). Salivary cortisol was used as an index of the psychological effects and caspase-14, collected from the stratum corneum, was used as a marker of environmental stress on the skin.

Objective

To demonstrate the possibility of evaluating the chronic influence of local air velocity from an air conditioner using noninvasive biomarkers.

Results

Local air velocity generated from the whole ceiling-type air conditioner where the subject's head was positioned was one-seventh that of the exhaust air conditioner. After exposure to the exhaust air conditioner for 5 days, salivary cortisol decreased significantly from morning to evening and skin caspase-14 gradually increased during the day. A significant increase in hydration index from the morning to the evening was found with the whole ceiling-type air conditioner.

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