Abstract
Dyke-Davidoff-Masson syndrome is a rare neurological condition characterized by intractable seizures, cerebral hemiatrophy with contralateral hemiparesis. Our patient, a 38-year-old female, presented following a left focal seizure with secondary generalization. She had a history of epilepsy, associated with left-sided hemiparesis, beginning at the age of 7. Physical examination showed increased left-sided tone and brisk reflexes, with an extensor plantar reflex on the left. The MRI brain showed features suggestive of Dyke-Davidoff-Masson syndrome: right-sided cortical atrophy, calvarial thickening and dilated frontal sinus. Additional MRI findings were of right cerebral peduncle atrophy and left cerebellar atrophy. This case report intends to emphasize the importance of Dyke-Davidoff-Masson syndrome as an unusual cause of seizures in an adult complicated by poor social determinants of health, leading to its delayed diagnosis.