Multidomain cognitive training increases physical activity in people with Parkinson's disease with mild cognitive impairment

多领域认知训练可增加轻度认知障碍帕金森病患者的身体活动

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作者:Merle Bode, Patricia Sulzer, Claudia Schulte, Sara Becker, Kathrin Brockmann, Saskia Elben, Ann-Kristin Folkerts, Anja Ophey, Christian Schlenstedt, Karsten Witt, Lars Wojtecki, Jordi Evers, Walter Maetzler, Elke Kalbe, Inga Liepelt-Scarfone

Conclusion

Study data revealed that CT can increase physical activity in patients with PD-MCI, possibly due to effects on executive functions, which needs further investigation in larger sample sizes. Lower working memory performance and ADL impairment might be associated with a more inactive lifestyle in patients with PD-MCI.

Methods

Eighteen patients with PD-MCI of the TrainParC study were analyzed. Those patients received either a 6-week multidomain group CT or physical training (PT). Physical activity and sedentary behavior were assessed with wearable accelerometers worn up to seven days pre- and post-training.

Results

Patients in the CT group displayed significantly greater increases in active periods after training than patients assigned to PT. In the CT group, increases in executive functioning were associated with increases in active periods and decreases in active mean bout length after training. At pretest, reduced working memory correlated with longer sedentary mean bout length, and impairment in activities of daily living (ADL) correlated with a higher number of sedentary periods.

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