Controversies and challenges in research on urogenital schistosomiasis-associated bladder cancer

泌尿生殖系统血吸虫病相关膀胱癌研究中的争议与挑战

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Abstract

Urogenital schistosomiasis, infection with Schistosoma haematobium, is linked to increased risk for the development of bladder cancer, but the importance of various mechanisms responsible for this association remains unclear, in part, owing to lack of sufficient and appropriate animal models. New advances in the study of this parasite, bladder regenerative processes, and human schistosomal bladder cancers may shed new light on the complex biological processes that connect S. haematobium infection to bladder carcinogenesis.

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