Abstract
According to the American Cancer Society, breast cancer is the second largest cause of mortality among women after lung cancer. Women's death rates can be decreased if breast cancer is diagnosed and treated early. Due to the lengthy duration of manual breast cancer diagnosis, an automated approach is necessary for early cancer identification. This research proposes a novel framework integrating metaheuristic optimization with deep learning and feature selection for robustly classifying breast cancer from ultrasound images. The structure of the proposed methodology consists of five stages, namely, data augmentation to improve the learning of convolutional neural network (CNN) models, transfer learning using GoogleNet deep network for feature extraction, selection of the best set of features using a novel optimization algorithm based on a hybrid of dipper throated and particle swarm optimization algorithms, and classification of the selected features using CNN optimized using the proposed optimization algorithm. To prove the effectiveness of the proposed approach, a set of experiments were conducted on a breast cancer dataset, freely available on Kaggle, to evaluate the performance of the proposed feature selection method and the performance of the optimized CNN. In addition, statistical tests were established to study the stability and difference of the proposed approach compared to state-of-the-art approaches. The achieved results confirmed the superiority of the proposed approach with a classification accuracy of 98.1%, which is better than the other approaches considered in the conducted experiments.