In Vitro Evaluation of the Antimicrobial Properties of Periodontal Barrier Membranes in Guided Bone Regeneration

体外评价牙周屏障膜在引导骨再生中的抗菌性能

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Abstract

OBJECTIVE: To compare the antimicrobial efficacy of three commercially available membranes (Jason®, Biogide®, and Lumina PTFE®) in inhibiting the growth of Enterococcus faecalis in vitro. MATERIAL AND METHODS: Thirty blood-agar petri plates were inoculated with E. faecalis and divided into three groups (n = 10) based on the barrier membrane tested: Group I (Jason®), Group II (Biogide®), and Group III (Lumina PTFE®). After 48-72 hours of incubation, the zones of inhibition surrounding the membranes on the plates were measured. At a significance level of P < 0.01 ANOVA was used for statistical analysis. RESULTS: Biogide® (Group II) demonstrated the highest antimicrobial activity with a mean zone of inhibition of 12.0 mm, followed by Jason® (Group I) with 10.5 mm. Lumina PTFE® (Group III) showed the least antimicrobial efficacy with a mean of 8.2 mm (P = 0.023). CONCLUSION: Biogide® exhibited the highest antimicrobial effectiveness, while Lumina PTFE® showed the least. Structural properties, such as membrane pore size and material composition, significantly influence bacterial adherence and effectiveness in GTR/GBR procedures, highlighting the need for optimized properties.

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