Out-of-hospital cardiac arrest outcomes, end-tidal carbon dioxide and extracorporeal cardiopulmonary resuscitation eligibility: New South Wales pilot data

院外心脏骤停预后、呼气末二氧化碳浓度和体外心肺复苏资格:新南威尔士州试点数据

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Abstract

OBJECTIVE: To describe on-scene times for out-of-hospital cardiac arrests (OHCA) transferred to hospital, the number of these that were extracorporeal cardiopulmonary resuscitation (ECPR) eligible and potential association between end-tidal carbon dioxide (ETCO(2) ) and survival so as to inform planned interventional studies. METHODS: Prospective cohort study of all OHCA, of suspected medical cause, where resuscitation was commenced and who were transported to participating hospitals from October 2020 to May 2021. RESULTS: One hundred and forty-nine OHCA were included. Forty-four (30%) patients survived to hospital discharge. Eighteen (8%) met ECPR inclusion criteria. Median on-scene time was 33 min (interquartile range [IQR] 24-44). Initial hospital ETCO(2) for non-survivors was 35 mmHg (IQR 19-50), survivors 36 mmHg (IQR 33-45); P = 0.215. No patient with an ETCO(2) less than 20 mmHg on hospital arrival to survived to hospital discharge. CONCLUSIONS: Average on-scene time did not differ on survivorship. A small number of transferred patients with OHCA were ECPR eligible. ETCO(2) less than 20 mmHg portends adverse prognosis. Our data will be used for future interventional studies.

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