Abstract
Refractory ventricular fibrillation (RVF) is a life-threatening arrhythmia that remains a challenge despite adherence to advanced resuscitation protocols. We present the case of a previously healthy 42-year-old man who experienced in-hospital cardiac arrest due to RVF following an acute inferolateral myocardial infarction. After multiple unsuccessful conventional defibrillation attempts, double sequential external defibrillation (DSED) with lateral decubitus position was employed as a salvage maneuver, resulting in return of spontaneous circulation (ROSC). The patient subsequently underwent successful thrombolysis and coronary revascularization with complete neurological and cardiac recovery. This case exemplifies the potential utility of DSED in treating RVF and emphasizes the importance of timely recognition, intervention, and post-resuscitation care in improving outcomes.