Abstract
The frequency of monkeypox outbreaks and the extent of the projected outbreaks in human populations have both steadily increased. This paper proposes Atangana-Baleanu fractional-order derivatives define in Caputo sense to investigate the kinetics of Monkeypox transmission in Ghana. We determine the stability of the recommended model's equilibrium points and basic reproduction number. The solution's existence and originality, as well as the model's Hyers-Ullam stability, are proven. The models basic reproduction number was found to be R (0) = 0.1940. The numerical simulation showed the fractional operator had an influence on the various compartments of the model. The dynamics of the disease in the community were shown to be influenced by fractional-order derivatives, and infections were eradicated within the first five (5) days when π = 0.2.