MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways

MetaboSignal:一种基于网络的代谢和信号通路拓扑分析方法,用于研究代谢表型调控

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Abstract

SUMMARY: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes. AVAILABILITY AND IMPLEMENTATION: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/. CONTACT: m.dumas@imperial.ac.uk . SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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