DisVis: quantifying and visualizing accessible interaction space of distance-restrained biomolecular complexes

DisVis:量化和可视化距离受限生物分子复合物的可及相互作用空间

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Abstract

We present DisVis, a Python package and command line tool to calculate the reduced accessible interaction space of distance-restrained binary protein complexes, allowing for direct visualization and quantification of the information content of the distance restraints. The approach is general and can also be used as a knowledge-based distance energy term in FFT-based docking directly during the sampling stage. AVAILABILITY AND IMPLEMENTATION: The source code with documentation is freely available from https://github.com/haddocking/disvis. CONTACT: a.m.j.j.bonvin@uu.nl SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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