LASER server: ancestry tracing with genotypes or sequence reads

LASER服务器:利用基因型或序列读取进行祖源追踪

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Abstract

SUMMARY: To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user-friendly interactive visualization of the results. AVAILABILITY AND IMPLEMENTATION: The LASER server is freely accessible at http://laser.sph.umich.edu/. CONTACT: dtaliun@umich.edu or wangcl@gis.a-star.edu.sg. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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