Poor clinical sensitivity of rapid antigen test for influenza A pandemic (H1N1) 2009 virus

2009 年甲型 H1N1 流感大流行病毒快速抗原检测的临床敏感性较差

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Abstract

Influenza A pandemic (H1N1) 2009 virus RNA was detected by reverse transcription-PCR in 144 clinical samples from Bonn, Germany. A common rapid antigen-based test detected the virus in only 11.1% of these samples. The paramount feature of rapid test-positive samples was high virus concentration. Antigen-based rapid tests appear unsuitable for virologic diagnostics in the current pandemic.

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