Prognostic Impact of Ultrasonography Features and (18)F-Fluorodeoxyglucose Uptake in Patients With Papillary Thyroid Microcarcinoma

超声检查特征和(18)F-氟脱氧葡萄糖摄取对乳头状甲状腺微小癌患者的预后影响

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作者:Ji Won Seo, Sang Hyun Hwang, Arthur Cho, Hye Sun Lee, Eun-Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Jin Young Kwak

Conclusion

In patients with PTMC, US features and SUV values on FDG-PET were not related to extrathyroid extension or LN metastasis. However, future studies with a larger sample size and longer follow-up should be performed to verify the results of this study.

Methods

This study included 74 patients with a single PTMC diagnosed pathologically. Patients underwent total thyroidectomy, or near-total thyroidectomy and staging thyroid US and positron emission tomography (PET) were performed prior to surgery. US features of thyroid nodules were reviewed retrospectively and the maximum standard uptake value (SUV) of nodules was semiquantitatively analyzed on (18)F-FDG PET/computed tomography (CT). Patients were followed-up for recurrence, which was defined as PTC on cytology

Results

Among the 74 patients, there was no recurrence. Thus we evaluated the correlation between SUV value and US features with poor prognostic factors of PTMC which included extrathyroid extension, central and lateral lymph node (LN) metastasis. However no clinicopathologic factors were associated with extrathyroid extension, central LN metastasis, or lateral LN metastasis.

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