Prophylactic Erythropoietin for Neuroprotection in Very Preterm Infants: A Meta-Analysis Update

预防性使用促红细胞生成素对极早产儿进行神经保护:一项荟萃分析更新

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Abstract

A meta-analysis update of randomized controlled trials investigating recombinant human erythropoietin suggests improved neurodevelopmental outcome in preterm infants. There was substantial heterogeneity, which could be ascribed to a single trial. Exclusion of this trial featuring a high risk of bias abolished heterogeneity and any effects of recombinant human erythropoietin treatment.

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