Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene

3-甲基胆蒽转化细胞中存在Kirsten鼠肉瘤病毒ras癌基因

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Abstract

Oncogenes have previously been reported in the DNAs of mouse fibroblast lines which had become transformed after in vitro exposure to the carcinogen 3-methylcholanthrene. These oncogenes are now shown to be versions of the cellular Kirsten ras gene and are therefore homologous to oncogenes detected in a variety of human tumor DNAs.

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