Antibacterial activity of copper-decorated CeO(2) nanoparticles and preparation of antifouling polyethersulfone surface

铜修饰CeO₂纳米粒子的抗菌活性及防污聚醚砜表面的制备

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Abstract

Cerium oxide NPs (nano-CeO(2)), with notable performance in various biological tests like redox activity, free radical scavenging, and biofilm inhibition, emerge as significant candidates to address issues in related areas. In this research, copper-decorated nano-CeO(2) (Cu@nano-CeO(2)) were first synthesized and then characterized using advanced techniques such as SEM-EDX, XRD, XPS, BET, and ICP-OES. The biochemical properties of the obtained Cu@nano-CeO(2) nanostructure and its performance in polyethersulfone (PES) membranes were thoroughly investigated in this research study. The free radical scavenging effect of Cu@nano-CeO(2) at 100 mg/L concentration was determined as 100 % with the same activity as the reference compounds Trolox and ascorbic acid. It enhanced 2.9-fold α-amylase enzyme activity at 50 mg/L. Plasmid DNA was completely degraded at 100 mg/L concentration. Cu@nano-CeO(2) provided significant inhibition against tested bacterial and fungal strains, especially Gram-positives than Gram-negatives and fungus. Anti-biofilm activity was determined against S. aureus and P. aeruginosa as 98.3 and 82.1 %, respectively. Furthermore, E. coli inhibition activity of PES/Cu@nano-CeO(2) 1.0 wt% membrane was determined as 100 %. Owing to the promising results obtained, we can suggest that Cu@nano-CeO(2) can be used in wastewater treatment.

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