Abstract
Infectious diseases have a huge health and economic burden globally. Vaccination has been found to be a crucial health intervention for diseases. The study aims to compare the drivers of vaccine uptake for influenza and dengue, and to understand the key drivers within each of the diseases in predicting vaccine uptake intentions. Data were collected from 1000 Singaporeans and Singapore permanent residents between the ages of 21 and 70 through face to face surveys. Overall, intention to get vaccinated was low for both diseases. Comparing the means between the knowledge and perceptions regarding influenza and dengue and their vaccine uptake intentions, perceived susceptibility was significantly higher for influenza than dengue; and perceived severity, knowledge of the disease, and benefits of the vaccine were significantly higher for dengue. Looking at the key drivers within the diseases, perceived susceptibility towards the diseases and benefits of the vaccine were positively associated with vaccination uptake intentions for influenza and dengue. Perceived barriers towards the vaccine were negatively associated with vaccine uptake for dengue. Programs conducted for public health promotion should focus on increasing the public's awareness of the susceptibility and seriousness of the diseases, and the benefits of getting vaccinated.