Abstract
The South East Asian initiative for elimination of kala-azar from the Indian subcontinent that began in 2005 is coming to fruition, with India in the last mile of elimination. This aptly timed commentary based on the publication of Pandey et al. (2025) entitled 'Kala-azar elimination in India: reflections on success and sustainability' highlights the complementarity of political commitment that ensured socioeconomic development, along with evidence-based operational research, that needs to be sustained for zero transmission to become a reality.