Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease known for its diverse clinical manifestations and multisystem involvement. While gastrointestinal symptoms are relatively common, pancreatitis remains an uncommon and potentially serious complication. We present the case of a 43-year-old female patient with a known history of SLE who was admitted with progressively worsening abdominal pain. Her evaluation revealed elevated lipase levels and radiological findings consistent with acute pancreatitis. She was managed with corticosteroids and supportive care, resulting in a complete recovery. This case highlights the importance of considering pancreatitis in patients with SLE presenting with abdominal pain and emphasizes the potential benefits of timely immunosuppressive treatment.