Abstract
We are reporting a rare case of collecting duct carcinoma in a 45years old male who was seeking for medical treatment of his persistent cough, dyspnea and weight loss. Chest x-ray revealed multiple focal opacities. Axial Contrast enhanced CT scan for the abdomen and pelvis showed right renal upper pole mass and D11 vertebral sclerotic metastasis. A core tissue biopsy for histopathology and immunohistochemistry was provisionally diagnosed as a clear cell carcinoma, however further immunohistochemical studies and histopathology consultation confirmed a Non-clear cell carcinoma, collecting duct carcinoma, that opens eyes on establishing earlier and accurate diagnosis of this rare tumor.