Abstract
Primary clear cell carcinoma of the urinary bladder is extremely rare reported only in case report or small case series. Due to its rarity, no consensus or recommendations are made on how to manage PCCUB and the pathogenesis of PCCUB is not clear. Based on histopathology and immunohistochemistry, a 58-year-old woman was diagnosed as PCCUB. The patient underwent radical cystectomy. Massive ascites and multiple lymph node metastasis occurred 6 months later. The diagnosis of PCCUB mainly depends on histopathology and immunohistochemistry. Although radical cystectomy is mainly applied for PCCUB treatment, the prognosis is poor in most cases.