Abstract
Spiradenoma is an uncommon benign neoplasm originating from eccrine sweat glands, typically characterized by a solitary tumor. Its diagnosis poses a challenge due to its morphological similarity to other solitary swellings. This report highlights the case of a 28-year-old male who presented with a solitary swelling on his right lower back. On ultrasonography, it was initially diagnosed as a sebaceous cyst. However, surgical excision and histopathological analysis revealed a well-defined grey-white nodule composed of basaloid cells organized in an alveolar and tubular pattern. This confirmed the diagnosis of eccrine spiradenoma, underscoring the critical importance of accurate diagnosis and management. The report emphasizes the significance of histopathology in differentiating eccrine spiradenoma from other solitary swellings and identifying its malignant potential. Furthermore, regular follow-up is necessary to prevent recurrence and potential metastasis. There is a need for further research to enhance the understanding and management of spiradenoma, along with its long-term outcomes.