Trichoblastic Carcinoma of the Right Clavicular Region: A Case Report With a Review of the Literature

右锁骨区毛母细胞癌:病例报告及文献复习

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Abstract

Trichoblastic carcinoma is a rare skin adnexal malignancy. It often resembles other skin malignancies in its gross and histopathological picture. While the definitive treatment for low-grade lesions is wide local excision, high-grade or inoperable lesions require chemo-radiation. It is important to ensure excision of an adequate clear skin margin while doing a surgical resection. The present case reports a 75-year-old male with a malignant skin lesion on his right clavicle. Magnetic resonance imaging showed it to involve the muscles and clavicle. Preoperative biopsy showed features of a trichilemmal carcinoma. A wide local excision of the part of the clavicle was done. A trapezius flap was mobilized to cover the defect. Histopathology and immunohistochemistry analysis confirmed the diagnosis of a low-grade trichoblastic carcinoma. This case report aims to emphasize that trichoblastic carcinoma can be considered one of the differentials of skin adnexal malignancies, and it needs a multidisciplinary approach to manage such rare malignancies.

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