Abstract
OBJECTIVE: To explore the efficacy and safety of successful interventional recanalization in patients with low NIHSS score acute cerebral infarction due to anterior circulation large vessel occlusion and influencing factors of futile recanalization. METHODS: A retrospective analysis was conducted on the clinical data of patients with acute cerebral infarction due to anterior circulation large vessel occlusion treated in our hospital from January 2019 to December 2023. Statistical methods such as chi square test, t-test and non parametric test for statistical analysis were used. RESULTS: A total of 445 patients were included in the study, including 32 in the low NIHSS score group and 413 in the non low NIHSS score group. There were statistical differences in NIHSS score at onset, preoperative ASPECT score, collateral circulation score, pathogenesis, effective recanalization rate, futile recanalization rate and 3-month postoperative mRS score between the two groups. There was no statistical difference in the incidence of complications such as symptomatic cerebral hemorrhage between the two groups. There were statistically significant differences in preoperative ASPECT score and collateral circulation score in terms of factors affecting futile recanalization in patients with low NIHSS score. CONCLUSION: Patients with acute cerebral infarction with anterior circulation large vessel occlusion and low NIHSS score had good therapeutic effect after successful interventional recanalization, and the safety was comparable to that of patients with non low NIHSS score. The factors that affecting futile recanalization in patients with low NIHSS score included preoperative ASPECT score and collateral circulation score.