Abstract
In recent years, advancements in dental implants have posed new challenges for the use of traditional orthopedic materials. This study prepared novel Ti-xNb-5Ta alloys via arc-melting and comprehensively evaluated the effects of Nb content on microstructure, mechanical properties, elastic modulus, electrochemical behavior, and in vitro performance. Interestingly, alloys with different Nb contents exhibited distinct properties. The results indicated that the 10 and 13 wt.% Nb alloys surpassed the TA4G surgical implant standard in strength while offering a lower elastic modulus and greater elongation. Electrochemical experiments showed that the corrosion resistance of the alloys improved with increasing Nb content. Furthermore, CCK-8 assay results, ALP semi-quantitative analysis, and RT-PCR demonstrated that Ti-xNb-5Ta alloys enhanced the early osteogenic differentiation of human bone marrow stromal cells (hBMSCs). This work not only reveals the potential of Ti-xNb-5Ta alloys as biomedical materials but also offers insights for developing novel biomaterials.