Abstract
Fluorinated colloidal nanosystems have attracted significant attention for their advantageous properties and potential applications in the biomedical field, especially in (19)F magnetic resonance imaging. These nanosystems are known for their high specificity, excellent biocompatibility, and ease of functional modification. Furthermore, they offer unique advantages for functional surface coating due to their surface performance and chemical resistance. This paper discusses recent developments in fluorinated colloidal nanosystems, including applications in biological detection (such as enzymes, proteins, pH levels, ions, reducing environments, and reactive oxygen species) and surface coating (such as self-cleaning, self-healing, antibacterial properties, anti-fogging, antifouling, and oil-water separation). This article also highlights current challenges and provides suggestions for future research directions in the field of fluorinated colloidal nanosystems.