Malaria Parasite Density Estimation using Actual and Assumed White Blood Cells Count in Children in Eastern Sudan

利用苏丹东部儿童实际和假定的白细胞计数估算疟原虫密度

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Abstract

BACKGROUND: Estimating malaria parasite count is needed for estimating the severity of the disease and during the follow-up. OBJECTIVE: This study was conducted to determine the malaria parasite density among children using actual white blood cell (WBC) and the assumed WBC counts (8.0 × 10(9)/l). METHODS: A cross-sectional study was conducted at New Halfa Hospital, Sudan. WBC count and count of asexual malaria parasite were performed on blood films. RESULTS: One hundred and three children were enrolled. The mean (SD) WBCs was 6.2 (2.9) cells × 10(9)/l. The geometric mean (SD) of the parasite count using the assumed WBCs (8.0 × 10(9)/l cells/μl) was significantly higher than that estimated using the actual WBC count [7345.76 (31,038.56) vs. 5965 (28,061.57) rings/μl,p = 0.042]. CONCLUSION: Malaria parasitemia based on assumed (8.0 × 10(9)/) WBCs is higher than parasitemia based on actual WBCs.

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