UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys

胎猴肝脏中的UDP-葡萄糖醛酸转移酶活性表现出两个发育阶段。

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Abstract

UDP-glucuronyltransferase was assayed in liver from adult rhesus monkeys and foetuses during late gestation. Activities toward 2-aminophenol, 5-hydroxytryptamine, 1-naphthol and 4-nitrophenol in the foetal liver ranged from 46 to 114% of adult values, whereas activities toward bilirubin, oestradiol and testosterone were less than 5% of adult values. This suggests that in primates UDP-glucuronyltransferase develops differentially in two clusters analogous to that in the rat.

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