A dinuclear ruthenium(II) complex as turn-on luminescent probe for hypochlorous acid and its application for in vivo imaging

一种双核钌(II)配合物作为次氯酸的“开启型”发光探针及其在体内成像中的应用

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作者：Liu,Zonglun,Gao,Kuo,Wang,Beng,Yan,Hui,Xing,Panfei,Zhong,Chongmin,Xu,Yongqian,Li,Hongjuan,Chen,Jianxin,Wang,Wei,Sun,Shiguo
期刊：Scientific Reports影响因子：3.900
时间：2016起止号：2016 Jun 30;6:29065
doi：10.1038/srep29065

Abstract

A dinuclear ruthenium(II) complex Ruazo was designed and synthesized, in which oxidative cyclization of the azo and o-amino group was employed for the detection of hypochlorous acid (HClO) in aqueous solution. The non-emissive Ruazo formed highly luminescent triazole-ruthenium(II) complex in presence of HClO and successfully imaged HClO in living cell and living mouse.

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