Ebola virus-like particles reprogram cellular metabolism

埃博拉病毒样颗粒重新编程细胞代谢

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作者:Huaqi Tang #, Yasmine Abouleila #, Anno Saris, Yoshihiro Shimizu, Tom H M Ottenhoff, Alireza Mashaghi

Key messages

• Ebola VLP can lead to metabolic alternations in endothelial cells and M1 and M2 macrophages. • Differential abundance of metabolites, mainly including fatty acids and sterol lipids, was observed after Ebola VLP exposure. • Multiple fatty acid-, steroid-, and amino acid-related metabolism pathways were observed perturbed.

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