Microbial Primer: Biosurfactants - the ABCs of microbial surface-active metabolites

微生物入门:生物表面活性剂——微生物表面活性代谢物的ABC

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Abstract

Microbial surfactants (biosurfactants) are low-molecular-weight amphiphilic secondary metabolites synthesized by a wide range of micro-organisms, including bacteria, yeasts and fungi. These compounds reduce surface and interfacial tension, promote emulsification and self-assemble into supramolecular structures such as micelles. Their remarkable structural diversity reflects the metabolic complexity of their microbial producers. In this primer, we outline shared features across biosurfactant-producing organisms, focusing on biosynthetic pathways, biological functions and regulatory mechanisms. The study of biosurfactants lies at the intersection of ecological, biotechnological and medical research, offering valuable insights into microbial ecology and promising avenues for sustainable innovation.

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