Abstract
BACKGROUND: Oral cancer is a leading cause of death in Pakistan, with a significant burden among rural populations. The primary risk factor for oral cancer in this region is the widespread use of smokeless tobacco (SLT). Despite international efforts to reduce tobacco consumption, SLT use remains prevalent. This study aimed to explore the experiences of a rural population with SLT use. METHODS: This qualitative study employed an exploratory, phenomenological approach in Gadap Town, a rural area near Karachi, to investigate how local socioeconomic realities and cultural norms influence SLT use. The interview transcripts of 28 SLT users (75% men, 25% women), purposively sampled, were included in the final analysis. Transcripts were thematically analysed after verbatim transcription and translation. RESULTS: Four major themes emerged: (1) Dynamics of addiction, including peer influence, familial patterns, and stress-related coping; (2) Risk perception, spanning awareness of oral cancer risk yet persistent usage; (3) Cessation journey, highlighting withdrawal challenges, emotional dependency, and limited professional support; and (4) Socioeconomic factors, notably the economic burden on households and calls for stricter regulation. Although participants recognized health hazards, they found cessation difficult due to emotional reliance and minimal external assistance. Socioeconomic factors, including the increased availability of unregulated, untaxed SLT products and limited free access to cessation support, were identified as critical influences. Participants emphasized the potential role of strict regulatory measures and relevant interventions in supporting cessation. CONCLUSION: This study highlights a critical disconnect between participants' awareness of the harmful effects of SLT and their actual behaviour in attempting cessation. Despite being aware of the health risks, such as oral cancer, participants often continued SLT use due to emotional dependency and socioeconomic factors. Interventions that focus on culturally relevant cessation strategies, stress and financial management, and strict regulatory enforcement are essential to bridge this gap to support behavioural change. CLINICAL TRIAL NUMBER: Not applicable.