Abstract
This case report highlights a rare incidence of acute angioedema triggered by an etchant during orthodontic treatment. It underscores the potential for commonly used dental materials to provoke allergic reactions. A 14-year-old female patient developed lip swelling, burning sensation, and localized pain shortly after etching. The reaction involved predominantly the upper lip, and the patient had no known history of allergy. Clinical signs included diffuse, non-pitting edematous swelling of the lips without systemic involvement. Acute allergic angioedema was diagnosed based on clinical evaluation. Immediate treatment with IV antihistamines and corticosteroids led to complete resolution. Chemical agents used in orthodontics can trigger hypersensitivity reactions. Early recognition, prompt management, and preventive strategies are essential to ensure patient safety during dental procedures.