From theory to practice: Careful construction and validation of a predictive model for colostomy for colorectal cancer peristomal irritant dermatitis

从理论到实践:构建和验证结肠造口术预防结直肠癌周围刺激性皮炎的预测模型

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Abstract

Peristomal irritant dermatitis (PIAD) is a common and difficult complication after stoma surgery, which brings both physical and psychological torture and seriously interferes with the normal recovery process and daily life. In-depth analysis of the influencing factors of PIAD and the establishment of a scientific and efficient prediction model have become the most urgent task to improve the quality of stoma care and the outcome of patients. Exploration of risk factors for postoperative development of PIAD in patients with colostomy for colorectal cancer and development of relevant predictive models. A total of 272 patients were collected in the study, of whom 58 had stoma prolapse; the patients enrolled in this study were randomly divided into a training set and a validation set according to a ratio of 7:3, of whom 190 were in the training set and 82 in the validation set. The patients' past medical history, stoma-related information and information related to the hospitalization period were collected separately to study the correlation factors affecting the emergence of PIAD in patients and to establish a prediction model. The potentially relevant factors were included in a 1-way logistic regression, and after analyzing the results: regular stoma clinic review, stoma site, ostomy flange fit, hypoproteinemia, anxiety, and radiotherapy were potential risk factors for PIAD, P < .05; The data obtained were further included in a multifactorial review: regular stoma clinic review, stoma site, ostomy flange fit or not, hypoproteinaemia, and anxiety were independent risk factors for PIAD (P < .05). This model provides a powerful tool for clinicians to identify patients at high risk of postoperative PIAD, which can help to take targeted preventive and interventional measures before the occurrence of dermatitis.

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