Abstract
This study investigates the impact of dermatological diseases on work activity, with a particular focus on potential gender differences. The primary objectives are to evaluate the severity of these conditions and their implications for job performance, productivity, and non-work-related daily activities. A cross-sectional analysis was conducted on employed patients with dermatological conditions between September 2021 and November 2023. Participants completed a new self-reported survey, including the Dermatological Diseases Work Impact Questionnaire (2DWIQ), along with two validated tools: the Work Ability Score (WAS) and the Work Productivity and Activity Impairment questionnaire. Participants were stratified by occupational category (blue- and white-collar workers). Statistical analyses were adjusted for factors influencing questionnaire outcomes, and the internal reliability of the 2DWIQ was assessed using Cronbach's α. The study included 417 participants (231 men and 186 women) affected by a dermatological disease primarily atopic dermatitis, psoriasis, and hidradenitis suppurativa. Women reported significantly higher levels of absenteeism, overall work impairment, and activity impairment compared to men. Additionally, they had lower WAS scores, indicating poorer work ability. Dermatological diseases have a greater impact on women, affecting both their work performance and daily lives. Gender-specific interventions are crucial to reducing the physical and psychological burden of these conditions and improving occupational health management.