Abstract
A 30-year-old Saudi female with well-controlled bronchial asthma presented to the emergency department with an acute exacerbation. Following administration of intravenous methylprednisolone, she experienced a severe anaphylactic reaction, necessitating intensive care management. This case highlights the rare but potentially life-threatening complication of steroid-induced anaphylaxis in asthma treatment and emphasizes the importance of prompt recognition and management.